Trial intelligence / Profile preview

ARTISTRY-2: subcutaneous ALKS 4230 alone and with pembrolizumab in advanced solid tumors

NL-OMON55159Phase 2Completed

Sponsor
Alkermes
Start
Dec 2021
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, open-label trial of nemvaleukin alfa and pembrolizumab in Nonhematologic neoplasms, non-small cell lung cancer (NSCLC), head and neck squamous cell carcinoma (HNSCC) and 5 more (5 arms), sponsored by Alkermes. Primary endpoints: Incidence and severity of treatment-emergent adverse events and Overall response rate. Started Dec 2021; status: completed.

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Drugs

nemvaleukin alfapembrolizumab
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Conditions

Nonhematologic neoplasmsnon-small cell lung cancer (NSCLC)head and neck squamous cell carcinoma (HNSCC)gastroesophageal junction adenocarcinomagastric adenocarcinoma

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