Trial intelligence / Profile preview

Blinatumomab plus AMG 404 in adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia

NL-OMON55298Phase 1Completed

Sponsor
Amgen
Start
Apr 2021
Modality
Vaccines & Immunotherapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of blinatumomab and zeluvalimab in acute lymphoblastic leukemia (ALL) and B cell acute lymphoblastic leukemia (B-ALL), sponsored by Amgen. Primary endpoints: Dose-limiting toxicities and Treatment-emergent adverse events. Started Apr 2021; status: completed.

02

Drugs

blinatumomabzeluvalimab
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Conditions

acute lymphoblastic leukemia (ALL)B cell acute lymphoblastic leukemia (B-ALL)

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