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Trial intelligence / Profile preview
Prednisolone effects in TLR4/TLR7 skin inflammation challenge model
NL-OMON55304Active, not recruiting
- Sponsor
- Centre for Human Drug Research
- Start
- Feb 2020
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Randomised, single-blind trial comparing Part A: imiquimod + prednisolone, Part B: lipopolysaccharide + prednisolone and Part B: lipopolysaccharide + placebo (3 arms). Primary endpoints: Adverse events, Vital signs and 11 more. Started Feb 2020; status: active, not recruiting.
02
Drugs
prednisoloneimiquimodlipopolysaccharide endotoxin
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