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Methotrexate effects on male fertility parameters in immune-mediated disease
NL-OMON55461Active, not recruiting
- Sponsor
- Erasmus MC
- Start
- Feb 2019
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
- Countries
- 1
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Overview
Open-label trial of methotrexate in rheumatoid arthritis (RA), undifferentiated arthritis (UA), spondyloarthritis (SpA) and 8 more (5 arms), sponsored by Erasmus MC. Primary endpoints: Quantification of methotrexate in seminal fluid and spermatozoa and Comparison of methotrexate concentration between naive and chronic users. Started Feb 2019; status: active, not recruiting.
02
Drugs
methotrexate
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Conditions
rheumatoid arthritis (RA)undifferentiated arthritis (UA)spondyloarthritis (SpA)psoriatic arthritis (PsA)ankylosing spondylitis (AS)
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