Trial intelligence / Profile preview

5-FU-induced gastrointestinal toxicity mechanisms in human colon

NL-OMON55582Active, not recruiting

Sponsor
Maastricht University
Start
Jun 2019
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
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Overview

Open-label trial of capecitabine in breast cancer and colorectal cancer (CRC) (3 cohorts), sponsored by Maastricht University. Primary endpoint: Whole genome transcriptomic response in colon epithelium. Started Jun 2019; status: active, not recruiting.

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Drugs

capecitabine
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Conditions

breast cancercolorectal cancer (CRC)

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