Trial intelligence / Profile preview

T-DM1 plus osimertinib for HER2-mediated resistance in EGFR-mutant NSCLC

NL-OMON55787Phase 2Active, not recruiting

Sponsor
Netherlands Cancer Institute
Start
Jan 2019
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of trastuzumab emtansine and osimertinib in non-small cell lung cancer (NSCLC), sponsored by Netherlands Cancer Institute. Primary endpoint: Objective response rate after 3 months. Started Jan 2019; status: active, not recruiting.

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Drugs

trastuzumab emtansineosimertinib
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Conditions

non-small cell lung cancer (NSCLC)

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