Trial intelligence / Profile preview

KEYMAKER-U03 Substudy 03B in advanced clear cell renal cell carcinoma

NL-OMON55940Phase 2Recruiting

Sponsor
Merck & Co.
Start
Jul 2023
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial of pembrolizumab, quavonlimab, lenvatinib and belzutifan in clear cell renal cell carcinoma (ccRCC) (4 arms), sponsored by Merck & Co. Primary endpoints: Occurrence of dose-limiting toxicity, Adverse events and 2 more. Started Jul 2023; status: recruiting.

02

Drugs

pembrolizumabquavonlimablenvatinibbelzutifan
03

Conditions

clear cell renal cell carcinoma (ccRCC)

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