Trial intelligence / Profile preview

VX-147 for APOL1-mediated proteinuric kidney disease

NL-OMON56156Phase 2Recruiting

Sponsor
Vertex Pharmaceuticals
Start
Feb 2023
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, randomised, double-blind trial in APOL1-mediated kidney disease (AMKD) comparing VX-147 with Placebo (2 arms). Primary endpoints: Percent change in urine protein-to-creatinine ratio from baseline at Week 48 and Estimated glomerular filtration rate slope. Started Feb 2023; status: recruiting.

02

Drugs

inaxaplin
03

Conditions

APOL1-mediated kidney disease (AMKD)

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