Trial intelligence / Profile preview

Encorafenib + cetuximab + pembrolizumab versus pembrolizumab in untreated BRAF V600E-mutant MSI-H/dMMR metastatic colorectal cancer

NL-OMON56187Phase 2Not yet recruiting

Sponsor
Pfizer
Start
Aug 2022
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial of encorafenib, cetuximab and pembrolizumab in colorectal cancer (CRC) (2 arms), sponsored by Pfizer. Primary endpoint: Progression-free survival. Planned start Aug 2022; status: not yet recruiting.

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Drugs

encorafenibcetuximabpembrolizumab
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Conditions

colorectal cancer (CRC)

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