Trial intelligence / Profile preview

KEYMAKER-U03 Substudy 03A in first-line advanced clear cell renal cell carcinoma

NL-OMON56282Phase 2Not yet recruiting

Sponsor
Merck & Co.
Start
Mar 2023
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial of pembrolizumab, quavonlimab, vibostolimab, lenvatinib and belzutifan in clear cell renal cell carcinoma (ccRCC) (4 arms), sponsored by Merck & Co. Primary endpoints: Dose-limiting toxicity, Adverse events and 2 more. Planned start Mar 2023; status: not yet recruiting.

02

Drugs

pembrolizumabquavonlimabvibostolimablenvatinibbelzutifan
03

Conditions

clear cell renal cell carcinoma (ccRCC)

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