Trial intelligence / Profile preview

Phase 1 study of AMG 199 in MUC17-positive advanced solid tumors

NL-OMON56431Phase 1Completed

Sponsor
Amgen
Start
Dec 2020
Modality
T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of amg 199 in gastric adenocarcinoma, gastroesophageal junction adenocarcinoma, colorectal cancer (CRC) and 1 more, sponsored by Amgen. Primary endpoints: Dose-limiting toxicities, Treatment-emergent adverse events and 2 more. Started Dec 2020; status: completed.

02

Drugs

amg 199
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Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinomacolorectal cancer (CRC)pancreatic adenocarcinoma (PDAC)

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