Trial intelligence / Profile preview

DYNE-101 multiple ascending dose study in myotonic dystrophy type 1

NL-OMON56459Phase 1Recruiting

Sponsor
Dyne Therapeutics
Start
Mar 2023
Modality
Antibody Conjugates → Antibody-Based Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
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Overview

Phase 1, randomised, double-blind trial of zeleciment basivarsen in myotonic dystrophy type 1 (DM1) (6 arms), sponsored by Dyne Therapeutics. Primary endpoint: Treatment-emergent adverse events. Started Mar 2023; status: recruiting.

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Drugs

zeleciment basivarsen
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Conditions

myotonic dystrophy type 1 (DM1)

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