Trial intelligence / Profile preview

ADAPT ALEC: standard-dose versus TDM-guided alectinib dosing

NL-OMON58650Phase 4Recruiting

Sponsor
University Medical Center Groningen
Start
Mar 2022
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
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Overview

Phase 4, randomised, open-label trial of alectinib in non-small cell lung cancer (NSCLC) and ALK-positive non-small cell lung cancer (2 arms), sponsored by University Medical Center Groningen. Primary endpoint: Progression-free survival. Started Mar 2022; status: recruiting.

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Drugs

alectinib
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Conditions

non-small cell lung cancer (NSCLC)ALK-positive non-small cell lung cancer

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