Trial intelligence / Profile preview

Sequential encorafenib + binimetinib followed by nivolumab + ipilimumab versus nivolumab + ipilimumab alone in BRAF V600-mutant advanced melanoma

NL-OMON58754Phase 2Active, not recruiting

Sponsor
European Organisation for Research and Treatment of Cancer
Start
Jun 2019
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of encorafenib, binimetinib, nivolumab and ipilimumab in melanoma (2 arms), sponsored by European Organisation for Research and Treatment of Cancer. Primary endpoint: Progression-free survival. Started Jun 2019; status: active, not recruiting.

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Drugs

encorafenibbinimetinibnivolumabipilimumab
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Conditions

melanoma

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