Trial intelligence / Profile preview

Alectinib or entrectinib versus durvalumab after chemoradiotherapy in biomarker-selected unresectable stage III NSCLC

NL-OMON58795Phase 3Completed

Sponsor
Roche
Start
Jul 2024
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised trial of alectinib, entrectinib and durvalumab in non-small cell lung cancer (NSCLC) (4 cohorts), sponsored by Roche. Primary endpoint: Progression-free survival. Started Jul 2024; status: completed.

02

Drugs

alectinibentrectinibdurvalumab
03

Conditions

non-small cell lung cancer (NSCLC)

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