Trial intelligence / Profile preview

Phase 1 study of intrathecal ALN-5288 in adults with Alzheimer's disease

NL-OMON58807Phase 1Recruiting

Sponsor
Alnylam Pharmaceuticals
Start
Apr 2026
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of ALN-5288 in Alzheimer's disease (AD) (3 arms), sponsored by Alnylam Pharmaceuticals. Started Apr 2026; status: recruiting.

02

Drugs

ALN-5288
03

Conditions

Alzheimer's disease (AD)

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