Trial intelligence / Profile preview

HERMES ziltivekimab in heart failure with preserved or mildly reduced ejection fraction and inflammation

NL-OMON58877Phase 3Active, not recruiting

Sponsor
Novo Nordisk
Start
May 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, double-blind trial in heart failure with mid-range ejection fraction (HFmrEF) and heart failure with preserved ejection fraction (HFpEF) comparing ziltivekimab + standard of care with placebo + standard of care (2 arms). Primary endpoints: Time to first composite heart failure endpoint and Total cardiovascular death and heart failure events. Started May 2023; status: active, not recruiting.

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Drugs

ziltivekimab
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Conditions

heart failure with mid-range ejection fraction (HFmrEF)heart failure with preserved ejection fraction (HFpEF)

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