Trial intelligence / Profile preview

Phase 1 open-label dose-escalation study of intracranial SI-053 added to standard of care in adults with newly diagnosed glioblastoma

NL-OMON58928Phase 1Not yet recruiting

Sponsor
Double Bond Pharmaceutical
Start
Jan 2025
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 1, open-label, single-arm trial of Temodex and temozolomide in glioblastoma (GBM), sponsored by Double Bond Pharmaceutical. Primary endpoints: Maximum tolerated dose and Dose-limiting toxicities. Planned start Jan 2025; status: not yet recruiting.

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Drugs

Temodextemozolomide
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Conditions

glioblastoma (GBM)

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