Trial intelligence / Profile preview

Single-dose open-label TX000045 study in pulmonary hypertension with HFpEF

NL-OMON58992Phase 1Completed

Sponsor
Tectonic Therapeutic
Start
Jul 2024
Modality
Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes, Hormonal Peptides → Native Peptides → Peptides, Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of TX000045 in combined post-capillary and pre-capillary pulmonary hypertension, Isolated postcapillary pulmonary hypertension (Ipc-PH) and heart failure with preserved ejection fraction (HFpEF), sponsored by Tectonic Therapeutic. Started Jul 2024; status: completed.

02

Drugs

TX000045
03

Conditions

combined post-capillary and pre-capillary pulmonary hypertensionIsolated postcapillary pulmonary hypertension (Ipc-PH)heart failure with preserved ejection fraction (HFpEF)

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