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CLL17 trial of ibrutinib versus fixed-duration venetoclax combinations in previously untreated CLL
NL-OMON59006Phase 3Active, not recruiting
- Sponsor
- University of Cologne
- Start
- Mar 2021
- Modality
- Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics
- Countries
- 1
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Overview
Phase 3, randomised, open-label trial in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) comparing Continuous ibrutinib monotherapy, Fixed-duration venetoclax + obinutuzumab and Fixed-duration venetoclax + ibrutinib (3 arms). Primary endpoint: Progression-free survival. Started Mar 2021; status: active, not recruiting.
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Drugs
ibrutinibvenetoclaxobinutuzumab
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Conditions
chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)
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