Trial intelligence / Profile preview

Linvoseltamab with or without carfilzomib versus standard-of-care regimens in relapsed/refractory multiple myeloma

NL-OMON59075Phase 3Not yet recruiting

Sponsor
Regeneron Pharmaceuticals
Start
Mar 2026
Modality
Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, Reversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
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Overview

Phase 3, randomised trial in multiple myeloma (MM) comparing Linvoseltamab monotherapy, Linvoseltamab + carfilzomib and Standard-of-care combination regimen (3 arms). Primary endpoints: Occurrence of treatment-emergent adverse events, Severity of treatment-emergent adverse events and 6 more. Planned start Mar 2026; status: not yet recruiting.

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Drugs

linvoseltamabcarfilzomib
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Conditions

multiple myeloma (MM)

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