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ACCLAIM-Lp(a): lepodisiran in adults with elevated lipoprotein(a)
NL-OMON59090Phase 3Active, not recruiting
- Sponsor
- Eli Lilly and Company
- Start
- Sep 2024
- Modality
- Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
- Countries
- 1
01
Overview
Phase 3, randomised, double-blind trial in atherosclerotic disease and lipoprotein(a) hyperlipoproteinemia (Lp(a)) comparing Lepodisiran with Placebo (2 arms). Primary endpoint: Time to first occurrence of any component of MACE-4. Started Sep 2024; status: active, not recruiting.
02
Drugs
lepodisiran
03
Conditions
atherosclerotic diseaselipoprotein(a) hyperlipoproteinemia (Lp(a))
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