Trial intelligence / Profile preview

MATTERHORN durvalumab plus FLOT in resectable gastric and gastroesophageal junction cancer

NL-OMON59121Phase 3Active, not recruiting

Sponsor
AstraZeneca
Start
May 2021
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, double-blind trial in gastric adenocarcinoma and gastroesophageal junction adenocarcinoma comparing Durvalumab + FLOT followed by adjuvant durvalumab with Placebo + FLOT followed by adjuvant placebo (2 arms). Primary endpoint: Event-free survival. Started May 2021; status: active, not recruiting.

02

Drugs

durvalumab
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Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinoma

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