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RIO trial of dual broadly neutralizing antibodies during analytical treatment interruption in early-treated HIV

NL-OMON59179Phase 2Recruiting

Sponsor
Imperial College London
Start
Oct 2025
Modality
Anti-infectious Disease mAbs → Neutralizing Antibodies → Monoclonal Antibodies → Antibody-Based Therapeutics, Naked Antibodies → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, randomised, double-blind trial of Teropavimab and zinlirvimab in human immunodeficiency virus infection (HIV) (2 arms), sponsored by Imperial College London. Primary endpoint: Time to viral rebound within 20 weeks after initial analytical treatment interruption. Started Oct 2025; status: recruiting.

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Drugs

Teropavimabzinlirvimab
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Conditions

human immunodeficiency virus infection (HIV)

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