Trial intelligence / Profile preview

AMAZE-lung: amivantamab + bevacizumab with continued osimertinib or lazertinib in EGFR-mutant advanced NSCLC after progression

NL-OMON59186Phase 2Completed

Sponsor
ETOP IBCSG Partners Foundation
Start
Jul 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of amivantamab, bevacizumab, osimertinib and lazertinib in non-small cell lung cancer (NSCLC) and Non-small cell lung cancer adenocarcinoma (NSCLC), sponsored by ETOP IBCSG Partners Foundation. Primary endpoint: Objective response rate. Started Jul 2023; status: completed.

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Drugs

amivantamabbevacizumabosimertiniblazertinib
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Conditions

non-small cell lung cancer (NSCLC)Non-small cell lung cancer adenocarcinoma (NSCLC)

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