Trial intelligence / Profile preview

CHOPIN trial of PHP with or without ipilimumab + nivolumab in metastatic uveal melanoma

NL-OMON59189Phase 2Recruiting

Sponsor
Leiden University Medical Center
Start
Jan 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial in intraocular melanoma comparing PHP alone with PHP + ipilimumab + nivolumab (2 arms). Primary endpoints: Safety and feasibility of PHP combined with ipilimumab and nivolumab and Progression-free survival at 1 year. Started Jan 2025; status: recruiting.

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Drugs

ipilimumabnivolumabmelphalan
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Conditions

intraocular melanoma

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