Trial intelligence / Profile preview

RAM-MS trial of HSCT versus high-efficacy disease-modifying therapy in aggressive relapsing-remitting multiple sclerosis

NL-OMON59216Phase 3Active, not recruiting

Sponsor
Helse Bergen
Start
Dec 2019
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised trial of antithymocyte immunoglobulin, alemtuzumab, cladribine and ocrelizumab in multiple sclerosis (MS) (2 arms), sponsored by Helse Bergen. Primary endpoints: No evidence of disease activity at 96 weeks and No evidence of disease activity at 240 weeks. Started Dec 2019; status: active, not recruiting.

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Drugs

antithymocyte immunoglobulinalemtuzumabcladribineocrelizumab
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Conditions

multiple sclerosis (MS)

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