Trial intelligence / Profile preview

LyRICX first-line treatment trial in advanced esophagogastric cancer

NL-OMON59284Phase 2Active, not recruiting

Sponsor
Amsterdam University Medical Center
Start
Jul 2019
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of nanoliposomal irinotecan, carboplatin, oxaliplatin, nivolumab, capecitabine and 2 more in gastroesophageal junction adenocarcinoma, gastric adenocarcinoma and esophageal adenocarcinoma (EAC) (3 arms), sponsored by Amsterdam University Medical Center. Primary endpoints: Progression-free survival 1 and Neurotoxicity. Started Jul 2019; status: active, not recruiting.

02

Drugs

nanoliposomal irinotecancarboplatinoxaliplatinnivolumabcapecitabine
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Conditions

gastroesophageal junction adenocarcinomagastric adenocarcinomaesophageal adenocarcinoma (EAC)

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