Trial intelligence / Profile preview

MK-3475-03B study of post-checkpoint inhibitor treatments for advanced clear cell renal cell carcinoma

NL-OMON59310Phase 2Completed

Sponsor
Merck & Co.
Start
Jun 2023
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of mk-4830, pembrolizumab, quavonlimab, favezelimab, lenvatinib and 1 more in renal cell carcinoma (RCC) and clear cell renal cell carcinoma (ccRCC) (2 arms), sponsored by Merck & Co. Primary endpoints: Number of participants with one or more dose-limiting toxicities, Number of participants with one or more adverse events and 5 more. Started Jun 2023; status: completed.

02

Drugs

mk-4830pembrolizumabquavonlimabfavezelimablenvatinib
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Conditions

renal cell carcinoma (RCC)clear cell renal cell carcinoma (ccRCC)

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