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First-line trastuzumab deruxtecan versus platinum + pemetrexed + pembrolizumab in HER2-mutant advanced NSCLC
NL-OMON59373Phase 3Active, not recruiting
- Sponsor
- AstraZeneca
- Start
- Feb 2022
- Modality
- Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
- Countries
- 1
01
Overview
Phase 3, randomised trial of trastuzumab deruxtecan in non-small cell lung cancer (NSCLC) (2 arms), sponsored by AstraZeneca. Primary endpoint: Progression-free survival by blinded independent central review. Started Feb 2022; status: active, not recruiting.
02
Drugs
trastuzumab deruxtecan
03
Conditions
non-small cell lung cancer (NSCLC)
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