Trial intelligence / Profile preview

LIBRETTO-431 selpercatinib versus platinum-pemetrexed with or without pembrolizumab in RET fusion-positive NSCLC

NL-OMON59435Phase 3Active, not recruiting

Sponsor
Eli Lilly and Company
Start
Jul 2020
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
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Overview

Phase 3, randomised, open-label trial of selpercatinib in non-small cell lung cancer (NSCLC) (2 arms), sponsored by Eli Lilly and Company. Primary endpoint: Progression-free survival. Started Jul 2020; status: active, not recruiting.

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Drugs

selpercatinib
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Conditions

non-small cell lung cancer (NSCLC)

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