Trial intelligence / Profile preview

CHOICES trial of dirocaftor/posenacaftor/nesolicaftor in adults with cystic fibrosis and rare CFTR mutations

NL-OMON59497Phase 3Withdrawn

Sponsor
University Medical Center Utrecht
Start
Nov 2022
Modality
Small Molecules
Countries
1
01

Overview

Phase 3, randomised, double-blind trial of dirocaftor, Posenacaftor and nesolicaftor in cystic fibrosis (CF) (2 arms), sponsored by University Medical Center Utrecht. Primary endpoint: Average percent predicted FEV1 after 4, 6, and 8 weeks. Planned start Nov 2022; status: withdrawn.

02

Drugs

dirocaftorPosenacaftornesolicaftor
03

Conditions

cystic fibrosis (CF)

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