Trial intelligence / Profile preview

HOVON 152 DLBCL: DA-EPOCH-R induction followed by nivolumab consolidation in newly diagnosed double-hit/triple-hit high-grade B-cell lymphoma

NL-OMON59517Phase 2Active, not recruiting

Sponsor
HOVON
Start
Jul 2018
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of nivolumab, rituximab, etoposide, prednisone, vincristine and 2 more in high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (HGBL-DH/TH) and diffuse large B-cell lymphoma (DLBCL), sponsored by HOVON. Primary endpoint: 12-month disease-free survival. Started Jul 2018; status: active, not recruiting.

02

Drugs

nivolumabrituximabetoposideprednisonevincristine
03

Conditions

high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (HGBL-DH/TH)diffuse large B-cell lymphoma (DLBCL)

Beyond the preview

Go deeper on NL-OMON59517.

Study design, results and competitive context are available in the Gosset platform where reported.

Study design & results

Available in the Gosset platform where reported.

Competitive context

Available in the Gosset platform where reported.

Bring the full picture into focus.

See how Gosset can support your research on NL-OMON59517.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call