Trial intelligence / Profile preview

TURANDORELA neoadjuvant nivolumab with or without relatlimab for resectable muscle-invasive bladder cancer

NL-OMON59525Phase 3Active, not recruiting

Sponsor
Netherlands Cancer Institute
Start
Feb 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, open-label trial in transitional cell carcinoma of the bladder (TCC) and muscle-invasive bladder cancer (MIBC) comparing nivolumab with nivolumab + relatlimab (2 arms). Primary endpoint: Pathological complete response. Started Feb 2024; status: active, not recruiting.

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Drugs

nivolumabrelatlimab
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Conditions

transitional cell carcinoma of the bladder (TCC)muscle-invasive bladder cancer (MIBC)

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