Trial intelligence / Profile preview

SONIA study of endocrine therapy sequencing with ribociclib in HR-positive/HER2-negative advanced breast cancer

NL-OMON59535Phase 3Active, not recruiting

Sponsor
Borstkanker Onderzoek Groep
Start
Nov 2017
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, Small Molecules
Countries
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Overview

Phase 3, randomised, open-label trial of ribociclib, fulvestrant, letrozole and anastrozole in breast cancer (2 arms), sponsored by Borstkanker Onderzoek Groep. Primary endpoint: Progression-free survival after two lines of treatment. Started Nov 2017; status: active, not recruiting.

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Drugs

ribociclibfulvestrantletrozoleanastrozole
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Conditions

breast cancer

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