Trial intelligence / Profile preview

Phase 1 dosimetry comparison of 177Lu-rhPSMA-10.1 versus Pluvicto in metastatic prostate cancer

NL-OMON59547Phase 1Completed

Sponsor
Blue Earth Therapeutics
Start
Feb 2025
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Beta-minus Emitters → Radiopharmaceuticals, Gamma Emitters → Radiopharmaceuticals
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of lutetium lu 177 vipivotide tetraxetan and lutetium (177Lu) rhPSMA-10.1 in prostate cancer (PCa), sponsored by Blue Earth Therapeutics. Primary endpoint: Tumor-to-kidney absorbed dose ratio comparison. Started Feb 2025; status: completed.

02

Drugs

lutetium lu 177 vipivotide tetraxetanlutetium (177Lu) rhPSMA-10.1
03

Conditions

prostate cancer (PCa)

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