Trial intelligence / Profile preview

Livmoniplimab + budigalimab plus platinum-doublet chemotherapy versus pembrolizumab plus platinum-doublet chemotherapy in untreated metastatic non-squamous NSCLC

NL-OMON59585Phase 3Active, not recruiting

Sponsor
AbbVie Inc.
Start
Apr 2025
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, open-label trial in Non-small cell lung cancer (NS-NSCLC) comparing Livmoniplimab + budigalimab + platinum-doublet chemotherapy with Pembrolizumab + platinum-doublet chemotherapy (2 arms). Primary endpoints: Best overall response of complete response or partial response and Overall survival. Started Apr 2025; status: active, not recruiting.

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Drugs

livmoniplimabbudigalimabpembrolizumab
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Conditions

Non-small cell lung cancer (NS-NSCLC)

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