Trial intelligence / Profile preview

DO-IT trial of intravenous thrombolysis in acute ischemic stroke patients with recent DOAC use

NL-OMON59685Phase 4Recruiting

Sponsor
Insel Gruppe
Start
Sep 2025
Modality
Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 4, randomised, open-label trial of tissue-plasminogen activator and tenecteplase in ischemic stroke (2 arms), sponsored by Insel Gruppe. Primary endpoint: Modified Rankin Scale shift at 90 days. Started Sep 2025; status: recruiting.

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Drugs

tissue-plasminogen activatortenecteplase
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Conditions

ischemic stroke

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