Trial intelligence / Profile preview

Vedolizumab with or without upadacitinib for moderately to severely active Crohn's disease

NL-OMON59696Phase 4Not yet recruiting

Sponsor
Takeda
Start
Mar 2025
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 4, randomised trial of vedolizumab and upadacitinib in Crohn's disease (2 arms), sponsored by Takeda. Primary endpoints: CDAI-defined clinical remission at Week 12 and Endoscopic response at Week 12. Planned start Mar 2025; status: not yet recruiting.

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Drugs

vedolizumabupadacitinib
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Conditions

Crohn's disease

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