Trial intelligence / Profile preview

Autogene cevumeran + atezolizumab + mFOLFIRINOX versus mFOLFIRINOX in resected pancreatic ductal adenocarcinoma

NL-OMON59712Phase 2Active, not recruiting

Sponsor
Genentech
Start
Nov 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial in pancreatic adenocarcinoma (PDAC) comparing Autogene cevumeran + atezolizumab + mFOLFIRINOX with mFOLFIRINOX alone (2 arms). Primary endpoint: Disease-free survival after randomization. Started Nov 2024; status: active, not recruiting.

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Drugs

autogene cevumeranatezolizumabmFOLFIRINOX
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Conditions

pancreatic adenocarcinoma (PDAC)

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