Trial intelligence / Profile preview

Divarasib versus sotorasib or adagrasib in previously treated KRAS G12C-positive advanced or metastatic non-small cell lung cancer

NL-OMON59753Phase 3Active, not recruiting

Sponsor
Roche
Start
Sep 2024
Modality
Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
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Overview

Phase 3, randomised, open-label trial in non-small cell lung cancer (NSCLC) comparing Divarasib with Sotorasib or adagrasib (2 arms). Primary endpoint: Progression-free survival. Started Sep 2024; status: active, not recruiting.

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Drugs

divarasibsotorasibadagrasib
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Conditions

non-small cell lung cancer (NSCLC)

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