Trial intelligence / Profile preview

IMPAHCT-FUL long-term extension of inhaled imatinib for pulmonary arterial hypertension

NL-OMON59787Phase 3Completed

Sponsor
Aerovate Therapeutics
Start
Nov 2022
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, open-label, single-arm trial of 4-chlorokynurenine in pulmonary arterial hypertension (PAH), sponsored by Aerovate Therapeutics. Primary endpoints: Safety and tolerability of AV-101, Change from baseline in 6-minute walk distance and 3 more. Started Nov 2022; status: completed.

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Drugs

4-chlorokynurenine
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Conditions

pulmonary arterial hypertension (PAH)

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Available in the Gosset platform where reported.

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