Trial intelligence / Profile preview

Phase 2 re-treatment study of ALXN2220 in transthyretin amyloid cardiomyopathy

NL-OMON59890Phase 2Active, not recruiting

Sponsor
Neurimmune
Start
Sep 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of cliramitug in amyloidotic transthyretin cardiomyopathy (ATTR-CM), sponsored by Neurimmune. Primary endpoints: Change from baseline to Visit 16 in cardiac magnetic resonance imaging and Change from baseline to Visit 16 in scintigraphy. Started Sep 2025; status: active, not recruiting.

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Drugs

cliramitug
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Conditions

amyloidotic transthyretin cardiomyopathy (ATTR-CM)

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