Trial intelligence / Profile preview

IMCISION II in advanced oral cavity squamous cell carcinoma

NL-OMON59978Phase 3Recruiting

Sponsor
Netherlands Cancer Institute
Start
Jan 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, open-label trial of nivolumab in Oral Mucosal Carcinoma and head and neck squamous cell carcinoma (HNSCC) (2 arms), sponsored by Netherlands Cancer Institute. Primary endpoints: Clinical complete response with organ preservation at 24 months and Recurrence-free survival non-inferiority. Started Jan 2026; status: recruiting.

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Drugs

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Conditions

Oral Mucosal Carcinomahead and neck squamous cell carcinoma (HNSCC)

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