Trial intelligence / Profile preview

Pelacarsen open-label extension after Lp(a)HORIZON

NL-OMON60026Phase 3Active, not recruiting

Sponsor
Novartis
Start
May 2026
Modality
Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Single-strand DNA → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Modified DNA Oligonucleotides → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics
Countries
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Overview

Phase 3, open-label, single-arm trial of pelacarsen in atherosclerotic disease, sponsored by Novartis. Primary endpoints: Treatment-emergent adverse events, Treatment-emergent serious adverse events and 4 more. Started May 2026; status: active, not recruiting.

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Drugs

pelacarsen
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Conditions

atherosclerotic disease

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