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Cobicistat-boosted venetoclax plus azacitidine in newly diagnosed AML patients unfit for intensive chemotherapy
NL-OMON60030Phase 2Suspended
- Sponsor
- HOVON
- Start
- Jan 2024
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 2, open-label trial of cobicistat, venetoclax and azacitidine in acute myeloid leukemia (AML) (2 arms), sponsored by HOVON. Primary endpoints: Pharmacokinetic equivalence and Overall survival. Started Jan 2024; status: suspended.
02
Drugs
cobicistatvenetoclaxazacitidine
03
Conditions
acute myeloid leukemia (AML)
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