Trial intelligence / Profile preview

FIREFLY-2: tovorafenib versus standard chemotherapy for first-line pediatric low-grade glioma with RAF alteration

NL-OMON60059Phase 3Active, not recruiting

Sponsor
Day One Biopharmaceuticals
Start
Jul 2023
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised trial in glioma comparing Tovorafenib monotherapy with Standard-of-care chemotherapy (2 arms). Primary endpoint: Overall response rate. Started Jul 2023; status: active, not recruiting.

02

Drugs

tovorafenib
03

Conditions

glioma

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