Trial intelligence / Profile preview

ALPINE trial of intra-arterial lutetium-177 PSMA-I&T for recurrent or progressive adult diffuse glioma

NL-OMON60267Phase 2Not yet recruiting

Sponsor
Erasmus MC
Start
Dec 2025
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Beta-minus Emitters → Radiopharmaceuticals, Gamma Emitters → Radiopharmaceuticals
Countries
1
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Overview

Phase 2 trial of lutetium Lu 177 PSMA I&T in diffuse midline glioma (DMG), astrocytoma, Oligodendroglioma (OG) and 1 more, sponsored by Erasmus MC. Planned start Dec 2025; status: not yet recruiting.

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Drugs

lutetium Lu 177 PSMA I&T
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Conditions

diffuse midline glioma (DMG)astrocytomaOligodendroglioma (OG)glioblastoma (GBM)

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