Trial intelligence / Profile preview

ARV-027 phase 1 study in healthy male participants and participants with spinal and bulbar muscular atrophy

NL-OMON60356Phase 1Recruiting

Sponsor
Arvinas
Start
Jan 2026
Modality
PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules, Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 1 trial of ARV-027 in spinal and bulbar muscular atrophy (SBMA) (2 arms), sponsored by Arvinas. Started Jan 2026; status: recruiting.

02

Drugs

ARV-027
03

Conditions

spinal and bulbar muscular atrophy (SBMA)

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