Trial intelligence / Profile preview

Pelacarsen cardiovascular outcomes trial in patients with elevated lipoprotein(a)

NL-OMON60368Phase 3Completed

Sponsor
Novartis
Start
Jun 2020
Modality
Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Single-strand DNA → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Modified DNA Oligonucleotides → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
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Overview

Phase 3, randomised, double-blind trial in cardiac morbidity and atherosclerotic disease comparing Pelacarsen with Placebo (2 arms). Primary endpoints: Expanded MACE in overall elevated lipoprotein(a) population and Expanded MACE in higher lipoprotein(a) subpopulation. Started Jun 2020; status: completed.

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Drugs

pelacarsen
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Conditions

cardiac morbidityatherosclerotic disease

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